February Insights- Healthy Lives, Healthy Planet: The Longevity-Sustainability Link

Join us as we explore microplastic-free packaging with Mr.Santosh Nagasamy, discover the link between sustainability & longevity & meet Dr. Subba Rao, whose research uncovers insights into skin aging.

Feb 25, 2025

From the community: Phitons – a pioneer in microplastic-free packaging solutions, combating plastic pollution and promoting sustainability

Phitons is an innovative company committed to developing microplastic-free packaging solutions, tackling the pressing environmental challenge of plastic pollution. Their mission is to create sustainable, eco-friendly alternatives that reduce the impact of packaging waste on the planet. Leading this initiative is Mr. Santosh Nagasamy, the CEO of Phitons, alongside a dedicated team striving to revolutionize the packaging industry. We had the opportunity to speak with Mr. Santosh and his teammate, Mr. Manoj, to gain insights into their vision, challenges, and the future of sustainable packaging.

LI: Can you share the inspiration behind Phitons and its mission in sustainable innovation?

Mr.Nagasamy: Phitons was born out of a critical discovery by our parent company, PHD, which detected traces of phthalates in its athlete clientele. Recognizing the health risks posed by toxic chemicals and microplastics, PHD set out to create packaging materials that would be safer for both people and the planet. From that starting point, Phitons was founded with a clear mission: to innovate in the materials space using only natural, non-toxic, and fully compostable compounds. We aim to ensure that what we produce not only safeguards human health but also contributes positively to the environment.

LI: What are some of the compostable products Phitons is currently developing, and how do they contribute to longevity?

Mr.Nagasamy: Our product line includes compostable polymers enhanced with natural soil-based multi-mineral fillers. Unlike conventional plastics that linger for centuries and degrade into harmful microplastics, our materials are designed to break down into biomass - enriching the soil rather than polluting it. By reducing exposure to toxic residues and chemicals, we support a healthier ecosystem, which in turn supports human health and longevity.

LI: What are the key challenges you face in sourcing and developing locally available raw materials?

Mr.Nagasamy: One of the primary challenges involves reliance on a critical raw material currently sourced from China. To reduce our dependency on imports, we’re actively investing in the development of this material internally, aiming to establish a reliable local supply chain. Additionally, we’re moving away from the common practice of using single-mineral fillers by incorporating a proprietary soil-based multi-mineral filler. This approach not only mitigates the risks associated with raw material sourcing but also improves the overall compostability and safety to the environment once they naturally compost.

LI: Have you conducted any studies or trials on the long-term impact of your materials in real-world applications?

Mr.Nagasamy: Our materials are made using PBAT, which is proven and certified to be naturally compostable. We enhance this polymer with our soil-based multi-mineral filler, ensuring that once it breaks down, it leaves behind biomass instead of microplastics or harmful residues.

LI: How do you see the sustainable materials industry evolving in the next decade?

Mr.Nagasamy: We anticipate a surge in consumer awareness and regulatory support pushing the industry toward more holistic and compostable solutions. As technology improves and collaborations grow, we foresee compostable alternatives becoming increasingly affordable, efficient, and widely adopted, ultimately helping to reduce the environmental and health impacts tied to conventional plastics.

LI: Are there any collaborations with academic institutions or research bodies to further your work?

Mr.Nagasamy: We collaborate with leading organizations and institutions to drive innovation and advance sustainable packaging solutions across various industries and applications. Our partnerships include:

University of Mysore

IITR Lucknow (Indian Institute of Toxicology Research)

CFTRI Mysore (Central Food Technological Research Institute)

NIO Goa (National Institute of Oceanography)

DFRL DRDO (Defence Food Research Laboratory)

LI: What role do policy and government regulations play in promoting compostable alternatives, and how do Phitons engage with policymakers?

Mr.Nagasamy: Policy and regulation are critical levers for driving the broad adoption of compostable materials. We advocate for legislation that supports compostable and non-toxic alternatives through industry coalitions and direct dialogue. We emphasize the importance of reducing microplastic pollution and champion standards that require truly earth-friendly materials. This collaborative approach helps create an environment where sustainable innovation can flourish, benefiting both human health and the planet.

Read more about Phitons: https://www.phitons.com/

Sustainability in Longevity – Towards a sustainable and resilient Singapore

Writers: Bhumika Garg, Suvani Rohatgi

Sustainability has shaped Singapore’s growth, balancing economic progress with environmental responsibility. Committed to the 2030 Agenda, it ensures clean air, water, and green spaces while advancing education, healthcare, and climate resilience. Through innovation and global collaboration, Singapore drives sustainable development and strengthens regional and international sustainability initiatives.

Since independence, Singapore has prioritized sustainable development, balancing economic growth with environmental and social well-being. Through strategic policymaking and a Whole-of-Government approach, it has transformed into a thriving, resource-efficient city while maintaining its Garden City vision. As ASEAN Chair, Singapore continues to drive innovation and resilience, aligning with global sustainability goals. Some of the Sustainable Develop Goals (SDGs) are as follows.

SDG1: End Poverty in All Its Forms Everywhere

Singapore strives for a fair, inclusive society by promoting employment, income growth, and access to education, housing, and healthcare. Support for low-income families includes CPF, WIS, subsidized housing, and financial aid through ComCare and Medifund for those in need.

SDG2: End Hunger, Achieve Food Security and Improved Nutrition, and Promote Sustainable Agriculture

With only 1% of land for agriculture, Singapore ensures food security through import diversification, local production, stockpiling, and internationalization. Collaboration with industry drives innovations like vertical farming, automation, and IoT-based precision agriculture. Efforts also focus on reducing food waste and supporting low-income households in meeting basic needs.

SDG3: Ensure Healthy Lives and Promote Well-being for All at All Ages

Singapore has one of the world's highest life expectancies with the accessibility of quality and affordable basic medical services for all, high standards of living, and a culture of healthy living. They have achieved this through various measures such as the 3M system – Medisave, Medishield, and Medifund that provides financial security and universal health coverage. They also emphasize preventive healthcare, vaccination programs, and managing chronic diseases like diabetes.

SDG4: Ensure Inclusive and Equitable Quality Education and Promote Lifelong Learning Opportunities for All

Singapore prioritizes broad-based, holistic education with well-trained teachers and the integration of information and communication technologies to aid learning. It ensures quality, affordable, and accessible education for all, including students with special needs through SPED (special education) schools. Beyond formal education, the SkillsFuture initiative promotes lifelong learning and upskilling to prepare individuals for an evolving job market

SDG5: Achieve Gender Equality and Empower All Women and Girls

Singapore upholds gender equality through its Constitution and policies ensuring equal opportunities, pay, and parental leave. With high female literacy and employment, strong legal frameworks combat domestic violence, while initiatives like the Diversity Action Committee promote women in leadership.

SDG6: Ensure Availability and Sustainable Management of Water and Sanitation for All

Despite water scarcity, Singapore ensures universal access to clean water and sanitation through its "Four National Taps" strategy—local catchments, imports, desalination, and NEWater. Advanced technologies, conservation policies, and public education support its vision of a “City of Gardens and Water.”

SDG 7: Ensure Access to Affordable, Reliable, Sustainable and Modern Energy for All

It promotes access to sustainable energy. Efforts include expanding electricity access, enhancing grid reliability, diversifying energy sources with LNG and solar, and fostering innovation in energy storage. Policies focus on efficiency, carbon tax, and regulatory frameworks. Future opportunities lie in renewable energy, infrastructure planning, and international cooperation to ensure secure and affordable energy.

SDG 8: Promote Sustained, Inclusive, and Sustainable Economic Growth, Full and Productive Employment, and Decent Work for All

Sustained economic growth relies on industrialization, workforce upskilling, and innovation. Key strategies include export-oriented policies, economic restructuring, and digital transformation. Initiatives supporting employment adaptability and sustainable tourism enhance workforce resilience.

SDG 9: Build Resilient Infrastructure, Promote Inclusive and Sustainable Industrialisation and Foster Innovation

Sustainable industrialization is driven by infrastructure development, innovation, and SME support. Investments in transport, digital connectivity, and R&D boost economic growth. High-tech manufacturing, enterprise scaling, and public-private partnerships enhance competitiveness. Initiatives like Model Factories and RIE2020 promote advanced manufacturing and innovation, ensuring long-term resilience in line with SDG 9’s goals of industry, innovation, and infrastructure.

SDG 10: Reducing Inequality Within and Among Countries

It aims to reduce inequality by ensuring social mobility, economic inclusion, and access to quality education, healthcare, and housing. Policies support low-income groups through wage supplements, lifelong learning, and social security. Initiatives like KidSTART provide early childhood support to break poverty cycles. Risk-pooling schemes ensure financial security, fostering an inclusive and resilient society.

SDG 11: Make Cities and Human Settlements Inclusive, Safe, Resilient and Sustainable

The Sino-Singapore Tianjin Eco-city showcases sustainable urban development through green buildings, renewable energy, and eco-friendly infrastructure. Guided by key sustainability metrics, it promotes resilient communities, green transport, and resource conservation. The World Cities Summit fosters global collaboration, innovation, and governance to create inclusive, safe, resilient, and sustainable cities.

SDG 12: Ensure Sustainable Consumption and Production Patterns

It promotes resource efficiency, waste reduction, and circular economies. Key strategies include the 3Rs (Reduce, Reuse, Recycle), e-waste and packaging waste management, food waste reduction, and hazardous waste control. Industry collaboration, public engagement, and innovative technologies drive sustainability, ensuring long-term environmental and economic benefits while minimizing landfill dependence.

Singapore’s success in sustainable development stems from its forward-thinking approach, integrating technology, education, and conservation into its policies. With initiatives like the “Four National Taps” for water security, green urban planning, and fostering innovation, Singapore has created a livable, resilient city. Its commitment to climate action, inclusive growth, and addressing future challenges like an aging population has set a global benchmark.

India can adopt similar strategies by focusing on education, skill development, and embracing technology for sustainable agriculture and water management. Strengthening policies on renewable energy, climate resilience, and urban planning, along with collaborative efforts, will drive India toward a sustainable, healthy future.

Bhumika Garg is a student pursuing a Masters degree in Life Sciences at IISc. She can be reached at bhumikagarg@iisc.ac.in.
Suvani Rohatgi is a student pursuing an M.tech in Bioengineering at IISc. She can be reached at suvanir@iisc.ac.in

Sustainability in Healthcare and the Food System: A Path to a Healthier Future

Writer: Shreya Vashista

Sustainability in healthcare and the food system is critical for ensuring both human and planetary well-being. As climate change, biodiversity loss, and resource depletion threaten global health, integrating sustainable practices into these sectors has become imperative. A sustainable food system emphasizes nutrient-rich, plant-based diets, and environmentally friendly agricultural practices, while sustainable healthcare focuses on reducing greenhouse gas emissions, minimizing medical waste, and adopting eco-conscious procurement and manufacturing. By aligning these efforts with global climate commitments, we can create a healthier future that benefits both people and the planet.

1. The ‘Safe Operating Space’ for Food Systems and Agriculture

Scientific research defines a "safe operating space" for food systems, where crossing environmental or dietary limits risks human and planetary health. Biodiversity loss and low vegetable intake can destabilize ecosystems and public health. Integrating sustainability into food policies supports global goals like the SDGs and the Paris Agreement. A key shift is increasing plant-based food consumption while reducing reliance on animal products for a more sustainable future.

Sustainable agricultural practices: Agriculture and fisheries must meet the growing population’s caloric needs while promoting dietary diversity for human and environmental health. Current practices favor high-yield crops for animal feed, reducing biodiversity. A shift toward diverse, nutrient-rich food production is essential. Sustainable intensification includes closing yield gaps, improving fertilizer and water efficiency, recycling nutrients like phosphorus, and adopting climate-smart strategies. These efforts aim to achieve net negative emissions, transforming the food system into a carbon sink by 2040, in line with the Paris Agreement’s climate goals.

2. Environmental Sustainability in Healthcare

Traditionally, discussions about sustainable healthcare have revolved around financial considerations. However, incorporating planetary health into these discussions is increasingly vital. Healthcare contributes significantly to greenhouse gas (GHG) emissions, necessitating measures that minimize environmental impact while ensuring effective medical care.

Reducing Greenhouse gas (GHG) emissions: A recent New England Journal of Medicine (NEJM) article proposed incorporating the carbon footprint (CFP) as an endpoint in randomized controlled trials (RCTs) used to evaluate the efficacy and safety of medical treatments. In the United Kingdom, high-GHG-emitting anesthetics and asthma inhalers are being phased out in favor of environmentally friendly alternatives. Such initiatives mark a shift toward eco-conscious medical practices.

Alternatives to single-use equipment: Refurbishing single-use medical devices, healthcare digital transformation, and integrating circular economy principles are vital measures to minimize medical waste and enhance resource efficiency. Preventive healthcare strategies, including early disease detection and management, not only reduce medical costs but also minimize the carbon footprint associated with advanced medical equipment usage. By prioritizing such disease prevention strategies, the healthcare sector can lower its environmental burden while improving patient outcomes.

3. Sustainable Manufacturing and Procurement in Healthcare

The pharmaceutical and medical device industries must enhance sustainability throughout their supply chains. This involves improving energy efficiency, reducing waste, and promoting the use of renewable energy in manufacturing processes. Encouraging investment in nature-positive initiatives and environmental restoration can further drive sustainability in the sector. Sustainable procurement standards are also critical. Healthcare institutions should prioritize environmentally friendly pharmaceuticals and medical devices, incorporating criteria that encourage waste reduction and recycling. Educating healthcare professionals and patients about the benefits of sustainable medical products can foster greater adoption and acceptance.

Linking Health and Environmental Benefits to Carbon Trading: Improving public health can reduce overall healthcare demand, subsequently decreasing the sector’s environmental footprint. In the future, public health improvements could be recognized as a factor in carbon trading markets, incentivizing policies that promote both health and environmental conservation. Strengthening integrated policies that align with these objectives will be instrumental in fostering a sustainable healthcare system.

4. Healthcare waste management

To mitigate environmental pollution and health risks, healthcare must prioritize sustainable packaging, improve waste management through recycling and reusable materials, and educate professionals on reducing environmental impact. Collaboration across sectors and global cooperation are key to fostering long-term sustainability in healthcare.

Healthcare institutions should transition to sustainable packaging materials and implement strategies to minimize waste. Medical waste management through proper segregation, recycling, and the use of reusable PPE can significantly reduce environmental harm. Training programs should improve awareness of when disposable materials are necessary, proper sterile equipment usage, and the environmental impact of pharmaceuticals, particularly in addressing antimicrobial resistance (AMR).

References: Click Here

Shreya Vashista is a student pursuing an M.tech in Bioengineering at IISc. She can be reached at shreyav@iisc.ac.in

Meet the Scientist

In this edition, we highlight the work of Dr. Subba Rao, whose research explores the complex mechanisms of intracellular transport and membrane organization in eukaryotic cells.

Dr. Subba Rao completed his Master’s at Banaras Hindu University and earned his Ph.D. from JNU, New Delhi/IMTECH, Chandigarh. He then pursued eight years of postdoctoral research at the University of Pennsylvania Institute for the Advanced Study of India. Currently, he is a Professor in the Department of Microbiology and Cell Biology at the Indian Institute of Science.

His lab investigates the role of small GTPases in endosomal dynamics for human pigmentation, lysosome function in skin homeostasis, and the molecular regulators of ER stress and lysosome function, with a focus on lysosomal storage diseases.

We are excited to feature him and his groundbreaking work in this edition.

LI: What led you to your career in aging research?

Dr. Subba Rao: My entire research career dealt with skin and its colour. It is the outermost and most evident organ of the human body. For the past eight years, our work has focused on skin organization, homeostasis, and hygiene. Notably, aging is more visibly apparent in the skin compared to other organs, making it a key indicator of the aging process. Thus, the opportunity to join the longevity program at IISc has made me interested in entering this domain. Note that it is a commercially competitive science for larger crowds. However, the science behind healthy aging is fascinating, which is where my interest lies. We are at a preliminary stage of understanding the epidermal layers of the skin in the context of aging and signaling.

LI: What are you currently working on?

Dr. Subba Rao: We are critically looking at the differences between differentiated and senescent cells in the epidermis. Our focus is on maintaining or reversing senescence in epidermal cells through the use of natural compounds, aiming to promote healthy and youthful skin. Moreover, this organ has an additional layer of complexity, such as the existence of a microbiome that requires another angle in the contest of skin health and hygiene. We are also exploring epidermal organization in skin-associated diseases.

LI: Your goal for the Longevity India Initiative?

Dr. Subba Rao: My goal is to identify small molecules to maintain or reverse the senescent status of keratinocytes in aged skin.

LI: List your personal health hacks.

Dr. Subba Rao: Start the day with yoga and a 1 KM run for fitness. Eat as required to maintain balance and nourishment.

The Longevity India RISE for Healthy Aging Conference is India’s first step toward building a future where aging isn’t just about living longer, but thriving: free from chronic disease, with bodies and minds that remain robust deep into old age.

RISE 2025 is a movement to bring together the brightest minds in science, industry, clinics, and policy to tackle aging at its roots. This is more than a conference - it’s the beginning of a movement.

Let’s RISE for a healthier, longer future!

Date: 10th - 12th March, 2025
Location: Indian Institute of Science (IISc)
Conference Agenda: Detailed Schedule

Don't miss out—secure your spot today: Click here to Register

Views expressed are personal and do not necessarily reflect those of Longevity India Initiative.

For more information or contributions that would benefit you and the Longevity India initiative, please write to longevity@iisc.ac.in